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Tinospora cordifolia (Willd.) Miers. (Giloe) plant is well known for its anti-spasmodic, anti-inflammatory, antipyretic properties and is being used in the treatment of gout, jaundice and rheumatism. Tinospora cordifolia is distributed throughout tropical Indian subcontinent and China. It is a shrub with large, glabrous, deciduous structure belongs to the family Menispermaceae.

The public databases and literature survey revealed very limited information with regard to genomic resources essential for judicious exploitation of Tinospora cordifolia. To this end, we have generated its entire transcript based database incorporating information of gene sequences and gene-based SSR (EST-SSR) or microsatellite markers.   SSR marker is very useful tool because of its co-dominant inheritance, multi-allelic variation and high reproducibility. Since EST-SSRs markers, designed in this database is derived from transcript sequences, it can have various applications in the field of genomics as well as understanding functional diversity of allelic variants, if any.  Moreover, it is equally useful for the generation of high density marker based genetic maps for gene/QTL discovery, phylogenetic studies and comparative genomics.

Citation: Singh, R.; Mahato, A.K.; Singh, A.; Kumar, R.; Singh, A.K.; Kumar, S.; Marla, S.S.; Kumar, A.; Singh, N.K. TinoTranscriptDB: A Database of Transcripts and Microsatellite Markers of Tinospora cordifolia, an Important Medicinal Plant. Genes 2022, 13, 1433. https://doi.org/10.3390/genes13081433

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This work is supported by Indian Council for Agricultural Research, Government of India, New Delhi